Figure 4.
Generalized linear models of spatial learning rates over the four training days for the radial water tread maze (RWTM) experiments in control mice (solid black line), exposed mice at 25 weeks of chronic exposure (solid gray line) and recovery mice (the same exposed mice nine weeks after cessation of toxin exposure; dashed gray line). The slopes of control and 25 week- exposed mice were significantly different. The slopes of the control and recovery mice were not significantly different from each other, but both were significantly different from the 25 week exposed mice (p < 0.05). The data reveal significant spatial learning impairment at 25 weeks of exposure that is no longer present after a nine-week recovery period of no toxin exposure.