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. 2016 Nov 4;5:1849454416663661. doi: 10.1177/1849454416663661

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© The Author(s) 2016

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Effect of patient serum on the tumorigenicity of BRCA1-deficient fibroblasts. Cells were cultured for 2 weeks in human serum as stated in the figure. Cells were injected subcutaneously in NOD/SCID mice. Four weeks after injection, growing tumors were excised and their volumes were calculated. Barres plot display xenotransplants obtained for each individual involved in the study. Values are mean ± SD (n = tumors obtained with 2–3 mice per group). NOD/SCID: nonobese diabetic/severe combined immunodeficiency; BRCA1: breast cancer 1.