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. 2016 Jan 1;5:11. doi: 10.5772/64148

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© 2016 Author(s). Licensee InTech.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 7. — Three possible IA exosomes eluted from beads; (a) antigen-antibody interaction may remain intact, while the antibody-bead linkers are disrupted during elution. Thus, antibodies are attached on the eluted IA exosomes, resulting in expanded sizes; (b) ideally, only the antigen-antibody interaction is affected and eluted IA exosomes will be the same as UC exosomes; (c) tetraspanins (CD9, CD63 and CD 81) are pulled out during the elution, causing IA exosomes' lost volume and partial contents.