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. Author manuscript; available in PMC: 2017 Aug 8.
Published in final edited form as: Mol Pharm. 2017 May 19;14(6):1852–1860. doi: 10.1021/acs.molpharmaceut.6b01015

Figure 5.

Figure 5

Representative images of the cell uptake of DOX (monomer) and the colloidal formulations of PPD–PLAC–PEG and fulvestrant–UP80 (tracked by BODIPY). SKOV-3 cells were used for all experiments. DOX monomer freely permeates the cell membrane, showing localized fluorescence within the cells’ nuclei. PPD and fulvestrant colloids show uptake only under serum-free conditions, with punctate fluorescence within the cell body. There is no evidence of cell uptake of colloids in serum-containing media. (Scale bar represents 30 μm.)