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. 2017 Aug 8;6:e28412. doi: 10.7554/eLife.28412

Figure 6. A novel C-terminal region in CaV2.1 α1 subunit regulates SV docking at the active zone and RRP size independent of Ca2+ signaling.

Figure 6.

Cartoon depicting truncated regions in our CaV2.1 α1 deletion mutants including the binding sites for CaVβ, CASK, RBP, RBP, RIM1/2, Mint-1 as well as PXXP motifs and the effects of truncations on ICa, SV docking, SV coupling as well as size of the fast and the total releasable synaptic vesicle pools. The critical region 2042–2061 is highlighted in grey.

DOI: http://dx.doi.org/10.7554/eLife.28412.013