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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: J Cell Physiol. 2016 Oct 26;232(6):1404–1414. doi: 10.1002/jcp.25634

Figure 3. Sperm hyperactivation but not total motility was affected by inh-172.

Figure 3

Human sperm were incubated for 5 hours in media that support capacitation in the presence or absence of inh-172 (5 μM), IBMX (0.2 mM) and dbcAMP (1 mM) and the motility parameters were analyzed by CASA. (A) Sperm motion parameter assessed by CASA. Mot: total motility; Prog: progressive motility; VAP: average path velocity; VCL: curvilinear velocity; VSL: straight-line velocity; ALH: amplitude of lateral head displacement; BCF: Beat frequency; STR: straightness; LIN: linearity. Values represent the mean ± SEM of 4 experiments ** vs inh-172 + dbcAMP/IMBX condition p<0.01. (B) Percentage of hyperactivated motility (%HA). Bars represent mean value ± SEM from at least 4 experiments. ** p<0.01.