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. Author manuscript; available in PMC: 2017 Nov 15.
Published in final edited form as: Nat Biotechnol. 2017 May 15;35(8):765–772. doi: 10.1038/nbt.3860

Table 2.

Human anti-HLA antibodies do not recognize HLA-E expressing cells.

B2M genotype of ESC-derived CD45+ cells

Serum anti-HLA type +/+ -/Edimer (pre-Cre) -/Edimer -/Etrimer c5 -/Etrimer c6
Positive Control ++++
A1
A1, 9, 11, 24, 25, 26, 36, 66, 6802 ++++
A1, 11, 26, 34, 36, 6601 +++
A1, 11, 36, 80
A2
A2, 68, 69
A3
A10, 28, 33
A11 ++
A11, 66 +
A23
A23, 24 ++++
A24 ++++
A68, 69
B5, 18, 35, 49, 53 ++++
B7
B7, 13, 41, 48, 60, 61
B7, 27, 42, 67
B7, 42
B7, 42, 55, 56, 67 ++++
B7, 48
B12, 35, 50, 62, 70, 75, 76, 77
B13, 27, 47, 60, 61
B35 ++++ ++
B35, 53 ++
B35, 49, 50, 53, 62, 70, 75, 77 ++++
B35, 75 +++
B41, 45, 50
B54, 55, 56 ++++
B55 +++
B60
B60