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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Dev Dyn. 2017 Jul 12;246(9):691–699. doi: 10.1002/dvdy.24531

Figure 5.

Figure 5

Inhibition of calcineurin (FK506-treatment) increases cx43 and reduces the frequency of evx1-positive rays. (A) Whole Mount ISH shows increased cx43 and decreased evx1 expression at the time of joint initiation (87 hpa) in FK506-treated fish versus DMSO (negative control). (B) FK506-treated fish (n= 3 fins) showed reduced frequency of evx1 positive fin rays compared to DMSO-treated fish (n = 4 fins). Statistically significant differences were determined by the student’s t-test where p < 0.01 (**). Error bars represent the standard deviation.