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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Dev Dyn. 2017 Jul 12;246(9):691–699. doi: 10.1002/dvdy.24531

Figure 7.

Figure 7

Reduced cx43 prior to joint formation increases the frequency of evx1-positive rays. (A) Whole mount ISH shows decreased cx43 expression and increased evx1 expression in the Tg(hsp70:miR-133a1)pd47 line at the time of joint initiation (87 hpa) in a1(+) (transgene-positive) versus a1(-) (non-transgenic). Bottom panels in A show evx1-positive fin rays across entire fins. (B) A higher percentage of fin rays in a1(+) transgenic fins showed expression of evx1 (n= 9 fins) compared to the a1(-) non-transgenic sibling (n = 9 fins). Both sp(+) and sp(-) fish were similarly treated for heat shock. Statistically significant differences were determined by the student’s t-test p < 0.01 (**). Error bars represent the standard deviation.