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. 2017 Jul 15;56(14):1825–1829. doi: 10.2169/internalmedicine.56.8040

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Copyright © 2017 by The Japanese Society of Internal Medicine

The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Figure 4. — Pathological findings of a gastric hyperplastic polyp obtained during endoscopic mucosal resection. (A) Histology of an endoscopic mucosal resection specimen from a large gastric hyperplastic polyp. [Hematoxylin and Eosin (H&E) staining; original magnification, ×2]. (B) Histology of the foveolar mucosa showing elongation and branching of the foveolae. (H&E staining; original magnification, ×100). (C) Immunohistochemical staining with OK-524 revealed the focal expression of gastrin receptor (GR) in the foveolar epithelium. (Original magnification, ×400). (D) 1: Immunohistochemical staining with OK-524 revealed no expression of GR in the foveolar epithelium of the gastric antrum mucosa as a negative control. 2: Immunohistochemical staining with OK-524 of parietal cells as a positive control. 3: Immunohistochemical staining with Anti-Proton Pump (H, K-ATPase α subunit) mAb of parietal cells.