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. 2017 Jul 15;56(14):1879–1884. doi: 10.2169/internalmedicine.56.7763

Table.

Clinical Features of Concurrent ATL and AML; Review of the Literature.

Patient
No.
Age/
gender
Subtype of
ATL
Subtype
of AML
Karyotype of AML Latent
Period
(m)
Preceding Oral VP-16 Other chemotherapy before AML Survival
(m)
Refs
Yes/No dose/
period (m)
1 49/M Smoldering M1 not evaluable 0 No - none 6 [5], [21]
2 64/M Acute M5 47,XY,+8 17 No none DXR, VP-16, CY, MTX 18 [5], [22]
3 37/M Chronic M2 46,XY,t(9;11)(p22;q23) 23 No - VCR, CY, DXR, THP-ADM, MCNU, VCM, VP-16, CBDCA 24 [5], [23]
4 36/F Smoldering M4 46, XX, t(15;17)(q22;q21) 0 No - none 30+ [5], [24]
5 74/F Chronic M4Eo 46,XY, inv(16)(p13q22) 17 Yes nr/3 none 18 [5], [13]
6 51/M Acute M2 46,XY,7q- 24 Yes 20,000 mg/16 Polypharmacy including high dose VP-16 nr [5], [14]
7 81/F Chronic M4 47,XX,+8,2p-,10p+ 2 No - none 29+ [5]
8 69/M Acute M2 46,XY,7q-,18p+ 26 No - CY, DXR, MCNU, THP-ADM, VP-16, CBDCA 39 [5]
9 63/F Lymphoma M4 46,XX,t(8;16)(p11;p13) 23 No - CY, DXR, VCR, MIT, MTX, VP-16 27 [5]
10 63/F Acute M4 46,XX,inv(9)(p11q13)c,
inv(16)(p13q22)
23 Yes nr/nr VCR, CY, DXR, MCNU, VCM, VP-16, CBDCA, Ara-C, MTX 30 [4]
11 64/M Acute M2 46,XY,t(8;21)(q22;q22) 21 No - VCR, CY, DXR, MCNU, VCM, VP-16, CBDCA, Ara-C, MTX, MST-16 nr [4]
12 50/F Lymphoma M2 46, X, t(X;10)(p11.2;p11.2),
t(5;12)(q31;p13),
inv(9)(p12q13)
63 Yes 10,000 mg/29 VCR, CY, DXR, MCNU, VCM, VP-16, CBDCA, Ara-C, MTX 66 [3]
Present case 61/F Chronic M2 46,XY,t(6;11)(q23,q27) 47 Yes 9,800 mg/41 none 58

VP-16: etoposide, VCR: vincristine, CY: cyclophosphamide, DXR: doxorubicin, MCNU: ranimustine, VDS: vindesine, CBDCA: carboplatin, Ara-C: cytarabine, MTX: methotrexate: THP-ADM: pirarubicin, MST-16: sobuzoxane, nr: not reported, m: months, refs: references