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. 2017 Aug 8;7:7512. doi: 10.1038/s41598-017-06387-6

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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NCMD typical clinical presentation in two selected individuals from family 3 (IV:3) and family 2 (IV:5). Each panel shows fundus autofluorescence and optical coherence tomography (OCT) images. Individual IV:3 (a,b) from family 3 shows a mild form of disease with relatively symmetrical, bilateral hyperfluorescent drusen-like deposits concentrated within the macular region and an otherwise normal OCT. Individual IV:5 (c,d) from family 2 presents with a well demarcated, relatively symmetrical and bilateral area of macular chorioretinal atrophy.