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. 2017 Aug 8;7:7574. doi: 10.1038/s41598-017-07095-x

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Changes of MAPKs protein expression in L_4–6 DRGs among groups. The representative bands for the expressions of p-ERK, p-JNK and p-p38 in DRG after injection of formalin. The quantitative data for the expression of each phospho-MAPKs. The fold change for the density of each phospho-MAPKs normalized to total MAPKs for each sample. The fold change of phospho-MAPKs levels in vehicle group was set at 1 for quantifications. Data were shown as mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 vs. vehicle.