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. 2017 Aug 8;7:7603. doi: 10.1038/s41598-017-07855-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Osteoclast fusion and migration are reduced when MYO10 expression is reduced. (A) Fusion index was calculated for day three osteoclasts using the formula fusion index (%) = total number of nuclei within giant cells/total number of nuclei counted × 100. (B) Adhesion of day two primary osteoclasts to vitronectin coated plates. (C) Transwell migration of day two primary osteoclasts. Experiments were performed at least three times and values represent the mean ± SD. *p < 0.05, ****p < 0.0001.