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. 2017 Aug 8;7:7602. doi: 10.1038/s41598-017-07632-8

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Verteporfin (VP) downregulates several members of the YAP-TEAD effectors in glioblastoma cells. SNB19 and LN229 cells were treated with vehicle (C), 2 µg/ml of VP (L) or 10 µg/ml of VP (H) for 24 hours protected from light at all steps. Western blot of protein extracts were probed for (A) c-myc, (B) axl, (C) survivin, (D) cyr-61, and (E) CTGF. Cropped blots are shown. Quantification of the blots relative to Coomassie blue staining, as a loading control, is on the right. (Experiment repeated 3 times, representative blot is shown here).