Skip to main content
. Author manuscript; available in PMC: 2017 Aug 9.
Published in final edited form as: Cancer Res. 2016 Jun 3;76(15):4516–4524. doi: 10.1158/0008-5472.CAN-16-0416

Figure 5.

Figure 5

A, total organ distribution of [125I] KX1 over the course of 6 hours (n = 4/time point). B, PARP-1 expression measured in HCC1937 and MDA-MB-231 tumors at time points up to 2 hours (n = 4/time point). C, ex vivo autoradiography of HCC1937 and MDA-MB-231 tumors at 2 hours. Olaparib-treated mice show a reduction in signal in HCC1937 but not in MDA-MB-231. D, in vivo competitive inhibition of [125I] KX1 using olaparib.*, signi of [125I] KX1 using olaparib cant change was measured in the organ.