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. 2017 Aug 8;10:4. doi: 10.1186/s13044-017-0039-0

Table 1.

The median (5th–95th percentile range) values of clinical and laboratory parameters in patients with newly onset of thyrotoxicosis during pregnancy

Gestational thyrotoxicosis
n = 30
New onset Graves’ thyrotoxicosis during pregnancy
n = 13
p value**
Onset age (years) 31.0 (24–40) 33.0 (25–37) 0.3257
Onset time (gestational weeks) 12.0 (8–15) 13.0 (10.8–17.8) 0.018
FT4 (ng/dl) 1.96 (1.61–2.52) 2.47 (1.67–3.94) 0.003
FT3 (pg/ml) 4.67 (3.76–6.67) 10.31 (4.72–30.00) <0.001
FT3/FT4 2.38 (1.98–3.06) 3.66 (2.40–7.47) <0.001
Thyroid volume (g) 17.1 (11.1–29.8) 27.4 (17.8–40.8) <0.001
Blood flow (%) 1.6 (0.8–6.6) 6.5 (1.4–18.8) 0.004
TRAb (IU/l) 1.3 (1.3–1.3)* 5.6 (5.6–32.0) <0.001
TgAb (IU/ml) 28.0 (28.0–42.9)* 28 (28–454.2)* 0.003
TPOAb (IU/ml) 16.0 (16.0–16.8)* 19.3 (16–441.6)* <0.01
Positive rate of TRAb (%) 0 100 <0.001
Positive rate of TgAb (%) 10.0 46.2 0.007
Positive rate of TPOAb (%) 3.3 46.2 <0.001

*Undetectable levels of TRAb, TgAb and TPOAb less than 1.3 IU/l, 28.0 U/ml and 16.0 U/ml were respectively calculated as 1.3, 28.0 and 16.0. **Comparisons of various parameters between GT and Gr during pregnancy were performed by the Mann-Whitney U-test