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. 2017 Aug 8;17:528. doi: 10.1186/s12885-017-3524-x

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Expression of proteins in the Hh- and PI3K/AKT/mTOR pathways in GOT1 tumors after sonidegib, ¹⁷⁷Lu-octreotate and combination treatment. Expression of Hh-related (GLI1, GLI2) and PI3K/AKT/mTOR-related (AKT, p-AKT, S6) proteins in tumors treated with sonidegib, ¹⁷⁷Lu-octreotate, or a combination of both pharmaceutical agents, and untreated controls, measured using western blot analysis. Representative immunoblots from each group are shown. + and - indicates treated and untreated, respectively