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. 2017 Aug 8;16:99. doi: 10.1186/s12933-017-0581-z

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — HMGB-1, OPG, HsCRP and IL-6 serum and severity of PAD (Fontaine’s II and Critical Limb Ischemia). HMGB-1 high-mobility group box 1, OPG osteoprotegerin, HsCRP high-sensitivity C-reactive protein, IL-6 interleukin-6. Statistical test performed with Student’s t test. Data are shown as serum levels ± standard deviation. *P < 0.001