Table 6.
Scenario analysis for men with low risk localised prostate cancer
| Age at diagnosis (Years) | ICER (Cost per QALY gained) | Dominance | |||
|---|---|---|---|---|---|
| AS vs WW | RP vs WW | AS vs RP | RP vs AS | ||
| Scenario one: using the 5% conversion rate | |||||
| 45 | - | $6,441 | - | - | AS was dominated by RP |
| 50 | - | $7,908 | - | - | AS was dominated by RP |
| 55 | - | $10,361 | - | - | AS was dominated by RP |
| 60 | - | $14,021 | - | - | AS was dominated by RP |
| 65 | - | $21,226 | - | - | AS was extended dominated by WW and RP |
| 70 | $31,135 | - | - | $33,140 | - |
| Scenario two: using new quality of life inputs | |||||
| 45 | $11,060 | - | - | - | RP was extended dominated by WW and AS |
| 50 | $12,602 | - | - | - | RP was extended dominated by WW and AS |
| 55 | $14,814 | - | - | - | RP was dominated by AS |
| 60 | $17,807 | - | - | - | RP was dominated by AS and by WW |
| 65 | $21,916 | - | - | - | RP was dominated by AS and by WW |
| 70 | $26,833 | - | - | - | RP was dominated by AS and by WW |
| Scenario three: using new costing inputs | |||||
| 45 | - | $5,324 | - | - | AS was dominated by RP |
| 50 | - | $6,613 | - | - | AS was dominated by RP |
| 55 | - | $8,793 | - | - | AS was dominated by RP |
| 60 | - | $12,332 | - | - | AS was extended dominated by WW and RP |
| 65 | $15,732 | - | - | $24,000 | - |
| 70 | $19,364 | - | - | $35,761 | - |
| Scenario four: using new quality of life inputs and costing inputs | |||||
| 45 | $11,254 | - | - | - | RP was extended dominated by WW and AS |
| 50 | $12,882 | - | - | - | RP was extended dominated by WW and AS |
| 55 | $15,248 | - | - | - | RP was extended dominated by WW and AS |
| 60 | $18,520 | - | - | - | RP was dominated by AS and by WW |
| 65 | $23,184 | - | - | - | RP was dominated by AS and by WW |
| 70 | $30,122 | - | - | - | RP was dominated by AS and by WW |
| Scenario five: using new quality of life values, costing values and the 5% conversion rate | |||||
| 45 | $22,904 | - | - | - | RP was extended dominated by WW and AS |
| 50 | $27,385 | - | - | - | RP was extended dominated by WW and AS |
| 55 | $33,790 | - | - | - | RP was extended dominated by WW and AS |
| 60 | $44,090 | - | - | - | RP was dominated by WW |
| 65 | $59,769 | - | - | - | RP was dominated by WW and by AS |
| 70 | $101,360 | - | - | - | RP was dominated by WW and by AS |
RP radical prostatectomy, AS active surveillance, WW watchful waiting