Table 1.
Characteristics of Adults Aged 20 to 79 Years With Elevated SBP Not Undergoing Blood Pressure Treatmenta
| Characteristic | All Adults
|
Adults With Prior CVD or Risk ≥15%
|
||
|---|---|---|---|---|
| SBP 120–139 mm Hg | SBP ≥140 mm Hg | SBP 120–139 mm Hg | SBP ≥140 mm Hg | |
| Total NHANES population, No. | 3472 | 1052 | 515 | 441 |
|
| ||||
| US population, No. in millions | 53.3 | 12.7 | 5.8 | 4.6 |
|
| ||||
| % Of US populationb | 25.8 (24.5–27.1) | 6.1 (5.6–6.7) | 2.8 (2.4–3.2) | 2.2 (1.9–2.6) |
|
| ||||
| SPRINT eligible | 5.4 (4.5–6.5) | 33.7 (30.1–37.5) | 27.0 (22.5–32.0) | 58.1 (51.3–64.6) |
|
| ||||
| HOPE-3 eligible | 4.4 (3.6–5.4) | 10.6 (8.2–13.5) | 10.6 (8.1–13.8) | 15.9 (11.7–21.3) |
|
| ||||
| Eligible for both HOPE-3 and SPRINT | 1.2 (0.9–1.7) | 7.5 (5.4–10.3) | 5.2 (3.5–7.7) | 13.8 (9.8–19.1) |
|
| ||||
| Age, mean (IQR), y | 45.3 (34.0–56.0) | 54.8 (46.0–65.0) | 62.3 (53.0–73.0) | 65.3 (59.0–73.0) |
|
| ||||
| Male sex | 61.6 (59.8–63.4) | 56.8 (53.4–60.1) | 71.2 (65.2–76.7) | 64.8 (58.2–70.9) |
|
| ||||
| African American | 10.1 (8.0–12.8) | 14.8 (11.3–19.1) | 6.9 (4.8–9.7) | 11.1 (7.5–16.2) |
|
| ||||
| Prior MI or angina | 3.5 (2.8–4.3) | 5.5 (3.9–7.8) | 32.0 (26.3–38.3) | 15.3 (11.1–20.6) |
|
| ||||
| Prior stroke | 1.1 (0.8–1.6) | 1.8 (1.1–3.1) | 10.3 (7.5–14.1) | 5.0 (2.9–8.5) |
|
| ||||
| Diabetes | 7.7 (6.8–8.7) | 13.7 (11.0–16.9) | 28.6 (23.0–34.9) | 28.0 (22.4–34.4) |
|
| ||||
| Heart failure | 0.9 (0.6–1.4) | 1.9 (1.0–3.4) | 7.2 (4.4–11.5) | 3.7 (1.9–7.0) |
|
| ||||
| BMI, mean (IQR) | 29.1 (24.7–32.4) | 29.2 (24.2–32.6) | 29.6 (25.2–33.1) | 29.1 (24.3–32.4) |
|
| ||||
| GFR, mean (IQR), mL/min/1.72 m2 | 91.4 (77.9–102.9) | 87.8 (74.0–99.9) | 81.5 (68.0–93.3) | 81.9 (68.3–96.5) |
|
| ||||
| Smoking | 26.5 (24.5–28.7) | 26.2 (22.8–29.8) | 38.1 (32.6–43.9) | 32.9 (27.0–39.4) |
|
| ||||
| Total cholesterol level, mean (IQR), mg/dL | 203.4 (175.0–228.0) | 209.0 (180.0–236.0) | 210.1 (177.0–237.0) | 212.9 (176.0–247.0) |
|
| ||||
| HDL-C, mean (IQR), mg/dL | 51.4 (40.0–59.0) | 54.3 (42.0–64.0) | 46.5 (37.0–54.0) | 52.2 (41.0–61.0) |
|
| ||||
| 10-y CVD riskc | 4.8 (0.7–6.2) | 11.6 (3.3–17.4) | 23.3 (17.3–27.3) | 24.7 (17.8–28.0) |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CVD, cardiovascular disease; GFR, glomerular filtration rate; HDL-C, high-density lipoprotein cholesterol; HOPE-3, Heart Outcomes Prevention Evaluation–3; HR, hazard ratio; IQR, interquartile range; MI, myocardial infarction; NHANES, National Health and Nutrition Examination Survey; SBP, systolic blood pressure; SPRINT, Systolic Blood Pressure Intervention Trial.
SI conversion factors: To convert total cholesterol and HDL-C to millimoles per liter, multiply by 0.0259.
Data are presented as percentage (95% CI) of column total, and continuous variables are presented as mean (IQR).
Percentage of population of nonpregnant US adults aged 20 to 79 years based on population extrapolations from the NHANES sample.
The 10-year risk of CVD by the pooled cohort equations.