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. 2017 Aug 8;12(8):e0181191. doi: 10.1371/journal.pone.0181191

Fig 8. Proposed signaling mechanism for the effects of 4'-HW on LPS-induced inflammation in RAW 264.7 macrophages.

Fig 8

4'-HW exerts its anti-inflammatory activity on RAW 264.7 macrophages by inhibiting ROS production, TAK1/IKK/NF-κB signaling pathway and reducing the phosphorylation of NF-κB, MAPKs and PI3/Akt signaling pathways.