Skip to main content
. 2017 Aug 8;12(8):e0182782. doi: 10.1371/journal.pone.0182782

Fig 1. Two globin-coupled diguanylate cyclases consist of three domains.

Fig 1

(A) Domain structures of EcGReg and BpeGReg. BLASTP searches against the non-redundant protein sequences database at the National Center for Biotechnology Information showed that EcGReg residues 5–153 represent a globin sensor domain and residues 268–458 represent a DGC domain, while BpeGReg residues 5–155 and residues 297–457 represent a globin sensor domain and a DGC domain, respectively. (B) Amino acid sequence alignment of five globin-coupled diguanylate cyclases: EcGReg, BpeGReg, AvGReg (Azotobacter vinelandii), SpGReg (Shewanella putrefaciens), and PccGReg (Pectobacterium carotovorum). The sequence order is based on the alignment. The residues highlighted in red are highly conserved and discussed in this work. The residues highlighted in blue are not highly conserved and discussed in this work. The line colors indicate the globin (orange), middle (green), and DGC (blue) domains.