Fig 3. Sensitivity of TCR-transduced T cells.

TCR-transduced CD8⁺ (A) or CD4⁺ (B) T cells expressing C18-specific, S20-specific, or S172-specific TCRs were co-cultured with T2 cells pulsed with decreasing peptide concentrations (effector to target ratio, E:T = 1:1). Each color represents one TCR. Cytotoxicity of effector cells was assessed by chromium release assay. Data are presented as mean values +/- SEM from triplicate co-cultures.