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. 2017 Aug 8;12(8):e0182936. doi: 10.1371/journal.pone.0182936

Fig 4. Recognition of different HLA-A*02 subtypes.

Fig 4

LCL with varying HLA-A*02 subtypes were loaded with HBV peptides (1 μM) and co-cultured with TCR-transduced C18-specific (A), S20-specific (B) or S172-specific (C) CD8+ T cells (E:T 1:1). T-cell activation was measured by IFN-γ ELISA. All donors, from which the TCRs originated, carried the HLA-A subtype *02:01 and therefore data were normalized to the recognition of the LCL with subtype *02:01 (set to 100%). The x-axis indicates the HLA-A*02 subtype of the target cells used (HLA-A*02:xx). Data are presented as mean values +/- SEM from triplicate co-cultures.