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. 2017 Jul 27;13(7):e1005686. doi: 10.1371/journal.pcbi.1005686

Fig 7. Fura-2 Ca2+ measurements of islets in 11 mM glucose and, as indicated, 50 μM of the membrane permeable 8-Br-cAMP.

Fig 7

(A) Ca2+ oscillations in wild-type islets persist with little or no change upon application of 8-Br-cAMP. Representative of 10 islets. (B) Ca2+ oscillations in SUR1-/- islets are terminated by 8-Br-cAMP, and Ca2+ is at a low level. Representative of 9 islets.