Table 2. . Tumor immunohistochemistry results: predicting progression-free survival at 38 weeks (median progression-free survival) from baseline HIF-1α.
| HIF-1α cut-point (% stained cells)† | Sensitivity | Specificity | 1 - specificity |
|---|---|---|---|
| 0 |
0.842 |
0.305 |
0.695 |
| 25 |
0.614 |
0.551 |
0.449 |
| 50 |
0.447 |
0.746 |
0.254 |
| 75 |
0.350 |
0.876 |
0.124 |
| 100 | 0 | 1.00 | 0 |
†The 25, 50 and 75% stain cells (percentage of tumor expression) represent the HIF-1α cut-points = 1, 2 and 3 in Figure 3, respectively. Data were reported as 0, 1, 2, 3, 4.