. Author manuscript; available in PMC: 2017 Aug 9.

Published in final edited form as: Br J Haematol. 2016 Mar 21;173(6):876–883. doi: 10.1111/bjh.14012

Table II.

Histopathological Bone Marrow Features of Monoclonal Gammopathy-Associated PRCA

Patient	Erythroid Precursors in Bone Marrow (%)	Plasma Cells in Bone Marrow (%)	Plasma Cell Expression by Immunohistochemistry			Total Bone Marrow Cellularity (%)	Reticulin Stain	Cytogenetics	BCR/ABL1Mutation Detected?	JAK2 V617F Mutation Detected?	CALR Type 1 and 2 Mutation Detected?	RTK Mutation Detected?
Patient	Erythroid Precursors in Bone Marrow (%)	Plasma Cells in Bone Marrow (%)	Light Chain Expression Restriction?	CCND1 Expression?	CD56 Expression?	Total Bone Marrow Cellularity (%)	Reticulin Stain	Cytogenetics	BCR/ABL1Mutation Detected?	JAK2 V617F Mutation Detected?	CALR Type 1 and 2 Mutation Detected?	RTK Mutation Detected?
1	7	30	Kappa	^*	Yes	60–80	2+	Normal	^*	No	No	No
2	8	20	Kappa	Yes	No	70–90	2+	Normal	No	No	No	No
3	9	15	No	^*	^*	90–100	2–3+	Normal	^*	^*	^*	^*
4	3	20	Lambda	^*	Yes	80	2–3+	Normal	No	^*	^*	^*
5	7	15	Lambda	^*	No	50	2–3+	Normal	^*	No	No	No
6	0	10	Kappa	^*	No	90–100	2–3+	Normal	^*	No	No	No
7	0	30	Kappa	^*	No	60	2–3+	Normal	^*	No	No	Yes KIT M541L
8	4	20	Lambda	No	Yes	65	2–3+	^*	No	No	No	No
9	7	10	No	^*	No	95–100	2–3+	Normal	^*	No	No	No
10	7	5	No	^*	No	70–80	2–3+	Normal	^*	No	No	No
11	4	15–20	No	^*	No	80–90	2+	Normal	^*	No	No	No
12	3	5–9	Lambda	^*	No	90–100	2–3+	inv (2)(p11.2q13)	No	^*	^*	^*

Test not performed.

PRCA, pure red cell aplasia; RTK, receptor tyrosine kinase