FIG. 7.
Maturation of engineered cartilage grown in vitro for up to 9 weeks. (A) Histological analysis (Alcian blue [left] and Picrosirius red [right]) as a function of time in culture (scale bar = 1 mm). (B) GAG and (C) collagen content as well as (D) equilibrium and dynamic modulus (E) derived from unconfined compression testing increased with duration of culture (*p < 0.05; **p < 0.01; ***p < 0.001; n = 10). Scatter plots showing the two individual studies are provided in Supplementary Figure S1. GAG, glycosaminoglycan. Color images available online at www.liebertpub.com/tea