FIG. 8.

Mechanical properties as determined from FE parameter optimization of indentation testing (white bars) and unconfined compression (black bars). Young's modulus, ksi, and permeability were computed for paired testing of (A) acellular agarose hydrogels of 4%, 6%, 8%, and 10% weight/weight (n = 6) and (B) engineered cartilage constructs grown in vitro for 3, 6, and 9 weeks (n = 10). *p < 0.05; **p < 0.01; ***p < 0.001. Scatter plots for agarose hydrogels are shown in Supplementary Figure S2 and scatter plots showing the two individual engineered cartilage studies are shown in Supplementary Figure S3.