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. Author manuscript; available in PMC: 2018 Jul 17.
Published in final edited form as: Birth Defects Res. 2017 Jul 17;109(13):1030–1038. doi: 10.1002/bdr2.23605

Figure 2. Unilateral vs. bilateral CL/P modifiers.

Figure 2

(A) Laterality (unilateral vs. bilateral) association results from the common-variant meta-analysis of Filipino and Chinese populations. (B) – (C) Regional association plots for 1q32 and 17q22 showing −log10(P-values) for SNPs with stronger association with unilateral CL/P (squares) and stronger association with bilateral CL/P (circles) based on the direction of the odds ratio. Plots were generated using LocusZoom (Pruim et al., 2010). The recombination overlay (blue line, right y-axis) indicates the boundaries of the LD-block. Points are color coded according to pairwise linkage disequilibrium (r2) with the index SNP.