Table 2. Pulmonary function tests in patients with LAM over time.

	Everolimus n = 29
	Week 24 n = 23	Week 96 n = 22	Week 192 n = 18
FEV1
Baseline, median (min, max), L	2.8 (1.2, 3.6)	2.55 (1.2, 3.5)	2.8 (1.2, 3.6)
Assessment, median (min, max), L	2.6 (1.3, 3.6)	2.55 (1.0, 3.5)	2.45 (0.9, 3.4)
Median percentage change from baseline	–3.45	–5.88	–9
FVC
Baseline, median (min, max), L	3.6 (1.8, 5.2)	3.6 (1.8, 5.2)	3.65 (2.1, 5.2)
Assessment, median (min, max), L	3.6 (2.0, 5.7)	3.6 (1.7, 5.4)	3.6 (2.1, 5.7)
Median percentage change from baseline	0	–1.25	–4.29
DLCO
Baseline, median (min, max), mmol/min/Kpa	6.01 (2.7, 9.6)	5.76 (2.7, 9.6)	6.01 (2.7, 9.6)
Assessment, median (min, max), mmol/min/KPa	5.74 (1.3, 8.2)	5.23 (2.2, 9.4)	5.95 (2.4, 7.0)
Median percentage change from baseline	–2.69	–10.19	–10.62

Abbreviations: DL_CO = diffusing capacity of the lung for carbon monoxide; FEV₁ = forced expiratory volume in 1 second; FVC = forced vital capacity.