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Top panel, ESI-Orbitrap MS analysis of recombinant Aβ42 show the presence of a dimeric species at 1290.52 M/Z and the lack of the Aβ42Δ39 peptide at 1472.42 M/Z. Bottom panel, ESI-Orbitrap MS analysis of synthetic Aβ42 showing the clear presence of the Aβ42Δ39 peptide at 1472.42 M/Z and many other contaminating species but undetectable levels of the 1290.52 M/Z dimer species.
