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. 2017 Aug 9;12(8):e0182751. doi: 10.1371/journal.pone.0182751

Fig 4. FAP is expressed at high levels throughout the synovium in biopsies of patients developing RA.

Fig 4

(A) Multicolour confocal microscopy images are shown for tissue staining at baseline with FAP (F11-24), podoplanin (D2-40), CD68 (Y1-82A), CD90 (Thy-1A1) antibodies followed by secondary agents, and nuclear (Hoechst) stain in a representative patient presenting with RA whose disease persisted. (B) Higher magnification, merged image. The region representing the lining layer is highlighted by a dotted line.