Table 3.

Unstimulated (UWS) and stimulated (SWS) whole salivary flow rate and composition in the patients with primary Sjögren's syndrome (pSS, n = 20) and the healthy controls (n = 20). Results are given in median (range).

	UWS			SWS
	pSS	Healthy controls	P-value	pSS	Healthy controls	P-value
Flow rate (ml/min)	0.02 (0.00–0.23) (n = 20)	0.39 (0.06–1.10) (n = 20)	<0.001	0.14 (0.01–1.66) (n = 20)	1.40 (0.54–2.82) (n = 20)	<0.001
Na+ (mM)	12.0 (8.0–47.0) (n = 11)	8.0 (4.5–17.0) (n = 20)	0.008	16.0 (8.0–59.0) (n = 12)	10.3 (5.5–30.0) (n = 20)	0.020
K+ (mM)	22.2 (5.1–48.0) (n = 11)	21.9 (6.8–33.4) (n = 20)	0.536	21.6 (15.2–34.6) (n = 12)	22.0 (11.5–26.5) (n = 20)	0.533
Total calcium (mM)	2.0 (1.3–3.2) (n = 7)	1.7 (0.5–2.8) (n = 19)	0.285	1.3 (0.7–1.9) (n = 12)	1.3 (0.8–2.5) (n = 20)	0.558
Cl- (mM)	25.8 (16.0–62.0) (n = 10)	18.3 (5.2–26.0) (n = 19)	0.003	22.6 (13.5–58.6) (n = 11)	16.1 (10.5–28.6) (n = 20)	0.037
Total phosphate (mM)	6.0 (1.2–15.0) (n = 9)	6.8 (2.4–11.7) (n = 19)	0.961	4.4 (2.4–8.5) (n = 11)	4.1 (1.6–11.5) (n = 20)	0.606
Total protein (mg/ml)	3.00 (1.52–8.84) (n = 8)	3.29 (1.36–6.25) (n = 19)	0.560	3.50 (0.421–8.93) (n = 12)	3.04 (1.23–5.54) (n = 20)	0.491
Total protein output (mg/min)	0.210 (0.06–0.80) (n = 8)	1.09 (0.50–2.38) (n = 19)	<0.001	0.95 (0.11–4.33) (n = 12)	3.88 (2.35–8.06) (n = 20)	<0.001
Amylase activity (μkat/l)	365 (0–4500) (n = 10)	980 (0–8940) (n = 19)	0.155	1490 (0–4080) (n = 12)	2280 (0–5890) (n = 20)	0.199

P-value obtained by Wilcoxon's rank sum test.