Table 1. Demographic characteristics and HIV-related parameters of patients at the time of HIV diagnosis.
| Overall | 1997–2002 | 2003–2008 | 2009–2012 | p* | |
|---|---|---|---|---|---|
| Number | 72 | 11 | 29 | 32 | |
| Male gender n(%) | 53(74) | 7(64) | 18(62) | 28(88) | 0.05 |
| Age median years (IQR) | 41(32–46) | 31(29–39) | 42(32–47) | 41(33–47) | 0.05 |
| Place of residence n(%) | 0.64 | ||||
| Local (Beijing, Tianjin and surrounding Hebei Provinc*) | 27(38) | 3(27) | 10(35) | 14(44) | |
| Other regions across China** | 45(63) | 8(73) | 19(66) | 18(56) | |
| Occupation n(%) | <0.001 | ||||
| Child/student | 3(4) | 0(0) | 3(10) | 0(0) | |
| Unemployed | 7(10) | 1(9) | 5(17) | 1(3) | |
| Manual laborer/farmer | 28(39) | 8(73) | 14(48) | 6(19) | |
| Professional, managerial, or administrative work | 26(36) | 2(18) | 6(21) | 18(56) | |
| Missing data | 8(11) | 0(0) | 1(3) | 7(22) | |
| Clinical department where diagnosis was made n(%) | 0.04 | ||||
| Emergency department | 19(26) | 0(0) | 7(24) | 12(38) | |
| Other departments*** | 53(74) | 11(100) | 22(76) | 20(63) | |
| Length of hospitalization median days (IQR) | 26(14–42) | 14(7–26) | 27(12–48) | 29(18–42) | 0.04 |
| Transmission n(%) | 0.001 | ||||
| Blood-borne | 21(29) | 6(55) | 13(45) | 2(6) | |
| Male-to-male | 12(17) | 0(0) | 3(10) | 9(28) | |
| Heterosexual | 9(13) | 2(18) | 3(10) | 4(13) | |
| Mother-to-child | 3(4) | 0(0) | 3(10) | 0(0) | |
| Unknown | 27(38) | 3(27) | 7(24) | 17(53) | |
| CD4+T cell count (n = 71) median cells/μL (IQR) | 24(6–101) | 26(3–132) | 27(5–88) | 22(6–143) | 0.96 |
| CD4+T cell count n(%) | 0.93 | ||||
| ≤ 50 cells/μL | 46(65) | 8(73) | 18(64) | 20(63) | |
| 51–100 cells/μL | 7(10) | 0(0) | 4(14) | 3(9) | |
| 101–200 cells/μL | 9(13) | 2(18) | 3(11) | 4(13) | |
| > 200 cells/μL | 9(13) | 1(9) | 3(11) | 5(16) | |
| HIV RNA (n = 49) median log10 copies/mL (IQR) | 5.08(4.51–5.46) | 5.08(4.47–5.62) | 5.14(4.40–5.66) | 4.96(4.54–5.37) | 0.94 |
| Number of patients with AIDS-defining conditions n(%) | 41(57) | 7(64) | 17(59) | 17(53) | 0.85 |
| Total cases of AIDS-defining conditions n **** | 47 | 9 | 19 | 19 | 0.77 |
| Pneumocystis jiroveci pneumonia n(%) | 31(66) | 5(56) | 13(68) | 13(68) | |
| Active tuberculosis n(%) | 7(15) | 3(33) | 2(11) | 2(11) | |
| Cytomegalovirus retinitis n(%) | 5(11) | 1(11) | 2(11) | 2(11) | |
| Esophageal candidiasis n(%) | 3(6) | 0(0) | 2(11) | 1(5) | |
| Pulmonary candidiasis n(%) | 1(2) | 0(0) | 0(0) | 1(5) | |
IQR, interquartile range; PUMCH, Peking Union Medical College Hospital; HIV, human immunodeficiency virus; AIDS, acquired immune deficiency syndrome
*p values are for comparisons among the three time intervals.
**Regional distribution of patients from other provinces across China from the highest to the lowest was: the North (15), the West (11), the Central (10), the East (8), and lastly, the South region (1).
***Numbers of patients diagnosed in other departments from the highest to the lowest were: Infectious Diseases (20), Pulmonology and Neurology (8 for each department), General Internal Medicine (5), Rheumatology (3), Pediatrics, Endocrinology and Gastroenterology (2 for each department), Ophthalmology, Oncology, and Traditional Chinese Medicine (1 for each department).
****Six patients had Pneumocystis jiroveci pneumonia plus other opportunistic infections (three with active tuberculosis, two with esophageal candidiasis, and one with pulmonary candidiasis).