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. 2017 Jul 28;11(7):e0005677. doi: 10.1371/journal.pntd.0005677

Table 2. Biological process gene ontology terms enriched for genes showing transcript abundance changes in either Rockefeller or Singapore in response to blood feeding or bacterial reintroduction.

GO ID GO name Expected Count Count Size p-value BH adj.
p-value
GO terms enriched for genes responding to blood feeding in Rockefeller but not in Singapore
GO:0046395 carboxylic acid catabolic process 0.562 6 26 1.47E-05 0.0034
GO:0044282 small molecule catabolic process 0.648 6 30 3.53E-05 0.0042
GO:0006082 organic acid metabolic process 4.646 15 215 5.49E-05 0.0042
GO:0042180 cellular ketone metabolic process 4.840 15 224 8.77E-05 0.0058
GO:0006631 fatty acid metabolic process 0.821 6 38 1.43E-04 0.0062
GO:0055114 oxidation-reduction process 15.148 30 701 1.62E-04 0.0062
GO:0034440 lipid oxidation 0.130 3 6 1.88E-04 0.0062
GO:0006081 cellular aldehyde metabolic process 0.151 3 7 3.24E-04 0.0089
GO:0032787 monocarboxylic acid metabolic process 0.951 6 44 3.28E-04 0.0089
GO:0006777 Mo-molybdopterin cofactor biosynthetic process 0.216 3 10 1.06E-03 0.0223
GO:0051189 prosthetic group metabolic process 0.216 3 10 1.06E-03 0.0223
GO:0006732 coenzyme metabolic process 2.161 8 100 1.36E-03 0.0273
GO:0006725 cellular aromatic compound metabolic process 1.253 6 58 1.47E-03 0.0283
GO:0042558 pteridine-containing compound metabolic process 0.562 4 26 2.16E-03 0.0384
GO:0051186 cofactor metabolic process 2.355 8 109 2.35E-03 0.0403
GO terms enriched for genes responding to blood feeding in Singapore but not in Rockefeller
GO:0006412 translation 10.419 27 303 4.15E-06 0.0020
GO:0055114 oxidation-reduction process 24.104 46 701 8.78E-06 0.0021
GO:0071843 cellular component biogenesis at cellular level 2.269 10 66 7.33E-05 0.0088
GO:0042254 ribosome biogenesis 1.513 8 44 1.05E-04 0.0101
GO:0001522 pseudouridine synthesis 0.413 4 12 5.42E-04 0.0434
GO terms enriched for genes responding to bacterial reintroduction in Rockefeller but not in Singapore
GO:0006082 organic acid metabolic process 1.085 7 215 7.64E-05 0.0026
GO:0042180 cellular ketone metabolic process 1.131 7 224 9.90E-05 0.0026
GO:0046394 carboxylic acid biosynthetic process 0.363 4 72 4.32E-04 0.0076
GO:0044283 small molecule biosynthetic process 0.399 4 79 6.16E-04 0.0092
GO:0044281 small molecule metabolic process 3.372 9 668 4.57E-03 0.0408
GO:0009089 lysine biosynthetic process via diaminopimelate 0.005 1 1 5.05E-03 0.0408
GO terms enriched for genes responding to bacterial reintroduction in Singapore but not in Rockefeller
GO:0070981 L-asparagine biosynthetic process 0.012 2 2 3.69E-05 0.0034
GO:0006528 asparagine metabolic process 0.018 2 3 1.10E-04 0.0051
GO:0006790 sulfur compound metabolic process 0.234 3 38 1.56E-03 0.0287
GO:0006082 organic acid metabolic process 1.323 6 215 1.81E-03 0.0287
GO:0005975 carbohydrate metabolic process 1.833 7 298 1.98E-03 0.0287
GO:0008652 cellular amino acid biosynthetic process 0.258 3 42 2.09E-03 0.0287
GO:0042180 cellular ketone metabolic process 1.378 6 224 2.23E-03 0.0287
GO:0009066 aspartate family amino acid metabolic process 0.074 2 12 2.34E-03 0.0287