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. Author manuscript; available in PMC: 2017 Aug 9.
Published in final edited form as: Biochim Biophys Acta. 2016 Apr 13;1862(7):1237–1246. doi: 10.1016/j.bbadis.2016.04.006

Fig. 7.

Fig. 7

A schematic diagram explains molecular mechanisms by which BMP-9 suppresses pathophysiology of obesity. Enhanced expression of FGF21 reduces a serum level of ALT as well as cholesterol and enhances brown adipogenesis, resulting in suppression of NAFLD and obesity.