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. 2017 Aug 8;9(2):710–723. doi: 10.1016/j.stemcr.2017.07.007

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Hub Genes of OPC and OLG Modules

Species-conserved OPC and oligodendrocyte differentiation-specific modules M5 (A) and M15 (B) were further examined to identify hub genes, which were expected to exert the largest influence on module constituents. The top 30 genes were selected based on the sum of intra-module connectivity between genes. The node size for each hub gene represents the relative hubness, and connection color indicates both the direction and degree of correlation with other hub genes.