Table 1.
Symbol | NCBI Entrez ID | Description | M15 Connectivity (Rank) | Day 4 versus Day 0 (No GF) |
Preserved in |
|||
---|---|---|---|---|---|---|---|---|
Log2 FC | q Value | M15D | M15C | M15A | ||||
BCAS1 | 8537 | breast carcinoma amplified sequence 1 | 17.0 (22) | 5.80 | 3.29 × 10−6 | X | ||
PPP1R16B | 26051 | protein phosphatase 1, subunit 16B | 21.0 (6) | 2.95 | 1.42 × 10−3 | X | ||
GNB4 | 59345 | G protein β4 | 7.7 (119) | 2.43 | 2.09 × 10−4 | X | X | |
HEXDC | 284004 | hexosaminidase D | 6.1 (159) | 2.08 | 2.88 × 10−3 | X | ||
MAN2A2 | 4122 | mannosidase α class 2A2 | 5.8 (168) | 1.93 | 2.28 × 10−3 | |||
POU2F1 | 5451 | POU class 2 homeobox 1 | 18.8 (12) | 1.78 | 2.04 × 10−3 | |||
DUSP22 | 100134291 | similar to MAPK phosphatase x | 7.8 (118) | 1.72 | 7.92 × 10−4 | |||
NPHP3 | 27031 | nephronophthisis 3 | 1.9 (368) | 1.58 | 1.56 × 10−3 |
Previously undescribed members of oligodendrocyte differentiation module M15 were identified that exhibited differential expression during oligodendrocyte differentiation, day 4 versus day 0 in differentiating conditions (log2 FC > 1, q value < 0.01). “X” indicates significant overlap between modules by FDR-corrected hypergeometric testing.