Table 1.
Description | Parameter name | Value |
---|---|---|
System size | 600 × 600 (hexagonal pixels) | |
Amplitude of cell-membrane fluctuations | 5 (dimensionless) | |
Cellular target volume | 40 pixels | |
Cellular elastic modulus | 9 (dimensionless) | |
Cellular target surface area | 25 pixels | |
Cellular membrane elastic modulus | 1.5 (dimensionless) | |
Elastic matrix’s Young’s modulus Elasticity-limited model Morphogen-limited model |
0.069 (dimensionless) 0.055 (dimensionless) |
|
Cell-cell interaction energy | 20 (dimensionless) | |
Morphogen diffusion coefficient | 1.19·10−14 m2·s−1 | |
Morphogen secretion rate | 0.23 s−1 | |
Morphogen concentration threshold | 0.1 pM | |
Time after division for cells to become quiescent | 2000 (Monte Carlo steps) | |
Mean refractory time | 200 (Monte Carlo steps) | |
Refractory time standard deviation | 50 (Monte Carlo steps) | |
Monte Carlo step time | 210 s | |
Model’s spatial scale | 8.6·10−13 m2 |