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. 2017 Jul 25;6:e25681. doi: 10.7554/eLife.25681

Table 1.

Parameter values for simulations of cellular proliferation in the utricle.

DOI: http://dx.doi.org/10.7554/eLife.25681.009

Description Parameter name Value
System size

N

600 × 600 (hexagonal pixels)
Amplitude of cell-membrane fluctuations

Tm

5 (dimensionless)
Cellular target volume

VT

40 pixels
Cellular elastic modulus

λVOL

9 (dimensionless)
Cellular target surface area

ST

25 pixels
Cellular membrane elastic modulus

λSURF

1.5 (dimensionless)
Elastic matrix’s Young’s modulus
Elasticity-limited model
Morphogen-limited model

E


0.069 (dimensionless)
0.055 (dimensionless)
Cell-cell interaction energy

JC

20 (dimensionless)
Morphogen diffusion coefficient

D

1.19·10−14 m2·s−1
Morphogen secretion rate

kM

0.23 s−1
Morphogen concentration threshold

[M]TH

0.1 pM
Time after division for cells to become quiescent

Tdiv

2000 (Monte Carlo steps)
Mean refractory time

Tref

200 (Monte Carlo steps)
Refractory time standard deviation

σref

50 (Monte Carlo steps)
Monte Carlo step time

dt

210 s
Model’s spatial scale

dA

8.6·10−13 m2