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. 2017 Aug 8;113(3):690–701. doi: 10.1016/j.bpj.2017.06.034

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© 2017 Biophysical Society.

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Emergence of innovative offspring is contingent on and constrained by parental genotypes. (A) Shown here is the number of innovative recombinant offspring resulting from linkage-based recombination between bacterial DNA donors specified on the vertical axis of (B), and the corresponding recipients specified on the horizontal axis of (C) (number of recombinants encoded according to the color legend). (B) Shown here is the total number of innovative recombinant offspring involving the donor genotype specified on the vertical axis. (C) Shown here is the total number of innovative recombinant offspring involving the recipient genotype specified on the horizontal axis.