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. 2017 Aug 8;113(3):702–713. doi: 10.1016/j.bpj.2017.06.046

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Fibroblast tissues exert large strains and rapidly align their surrounding matrix. (A) Percentage of unaligned fibers over time for tissues comprised of NIH3T3 fibroblasts. The mean ± SE of three independent experimental replicates is shown. (B) Radial strain over time exerted by tissues comprised of NIH3T3 fibroblasts. The mean ± SE of three independent experimental replicates is shown. (C) Confocal image of a representative fibroblast tissue at 6 h after seeding. (D) Confocal image of a representative fibroblast tissue at 24 h after seeding. The scale bar represents 50 μm. To see this figure in color, go online.