Table 4. Studies of sensitivity and specificity of tests for MCI vs. normal.
| MCI vs. normal-aging test | n, MCI | n, normal | n, total | Sensitivity | Specificity |
|---|---|---|---|---|---|
| CWL with CA-weighted scoring* | 95 | 119 | 214 | 94 | 89 |
| CWL total delayed-recall score* | 95 | 119 | 214 | 82 | 91 |
| Object delayed recall with proactive interference | 53 | 53 | 106 | 85 | 89 |
| Modified MMSE† | 24 | 52 | 76 | 83 | 90 |
| Cognitive Capacity Screening Exam (CCSE) | 47‡ | 267 | 314 | 74 | 85 |
| 84 | 267 | 351 | 88 | 84 | |
| MMSE + CCSE | 47‡ | 267 | 314 | 83 | 80 |
| DemTect | 97 | 97 | 194 | 80 | 92 |
| Computerized Dementia Screen (Korean) | 41 | 103 | 144 | 76 | 94 |
| Clock drawing test | 48 | 41 | 89 | 75 | 76 |
| MMSE | 24 | 52 | 76 | 71 | 85 |
| 47 | 267 | 314 | 61 | 80 | |
| 7-min test | 25 | 35 | 60 | 28 | ? |
| Functional activities questionnaire | 244 | 198 | 442 | 20 | 99 |
*
Data from the present study using the randomization validation method (see Methods).
†
The MMSE was modified by including multiple delayed recall trials.
‡
This MCI sample was restricted to those with a National Institute of Neurological Disorders and Stroke/Alzheimer's Disease and Related Disorders Association diagnosis of possible AD.