. Author manuscript; available in PMC: 2018 Aug 1.

Published in final edited form as: J Bone Miner Res. 2017 Jun 28;32(8):1750–1760. doi: 10.1002/jbmr.3166

Table 1.

Micro-computed tomography (μCT) parameters measured during fracture injury repair.

Measured Parameter	Unfractured		1.5 weeks post fracture		3 weeks post fracture

	Control (n=6)	Hox11 mutant (n=8)	Control (n=5)	Hox11 mutant (n=8)	Control (n=5)	Hox11 mutant (n=6)
Callus Volume (mm³)	0.45 (0.03)	0.52 (0.04)^*	1.81 (0.45)	2.75 (0.72)^*	1.74 (0.22)	1.59 (0.50)
Bone Volume (mm³)	0.32 (0.01)	0.35 (0.03)^*	0.52 (0.13)	0.78 (0.22)^*	0.57 (0.08)	0.57 (0.21)
BV/TV (%)	.71 (0.02)	0.67 (0.02)	.32 (0.18)	0.28 (0.03)	0.33 (0.05)	0.35 (0.05)
BMD (mg/cc)	839.6 (40.7)	740.2 (61.8)	486.0 (173.2)	424.1 (101.1)	511.3 (30.4)	480.2 (77.5)
BMC (mg)	.36 (0.01)	0.39 (0.05)	0.82 (0.15)	1.07 (0.31)	0.89 (0.08)	0.78 (0.32)
TMD (mg/cc)	977.0 (32.0)	905.6 (85.4)	935.3 (101.8)	860.7 (101.4)	838.0 (31.3)	792.5 (74.3)

Measured Parameter	6 weeks post fracture		12 weeks post fracture		21 weeks post fracture

	Control (n=5)	Hox11 mutant (n=6)	Control (n=5)	Hox11 mutant (n=4)	Control	Hox11 mutant (n=5)

Callus Volume (mm³)	1.45 (0.25)	1.61 (0.62)	0.99 (0.12)	1.52 (0.27)^*	ND	1.49 (0.16)^*
Bone Volume (mm³)	0.79 (0.13)	0.81 (0.28)	0.63 (0.10)	0.93 (0.04)^*	ND	0.86 (0.06)^*
BV/TV (%)	0.55 (0.07)	0.51 (0.05)	0.64 (0.04)	0.63 (0.09)	ND	0.58 (0.04)
BMD (mg/cc)	664.3 (83.7)	606.4 (60.2)	796.2 (49.3)	817.7 (104.3)	ND	751.2 (24.3)
BMC (mg)	0.96 (0.17)	0.97 (0.34)	0.79 (0.13)	1.22 (0.07)^*	ND	1.09 (0.12)^*
TMD (mg/cc)	896.8 (48.6)	866.9 (37.1)	1036.2 (26.4)	1054.0 (72.6)	ND	983.3 (57.1)

ND, no data collected. Parameters measured include callus volume, total bone volume, bone volume fraction (BV/TV), bone mineral density (BMD), bone mineral content (BMC), and tissue mineral density (TMD). Statistical analyses carried out by Students' T-test;

= p<0.05.