Table 4.
SNPs which showed association with super-shedding phenomena.
| Gene | Variant.ID | Location | Alleles | Freq_NS* | Freq_SS** | Consequence | p-value |
|---|---|---|---|---|---|---|---|
| APOA1 | rs384985356 | 15:27932563 | A/C | A, 50% | A, 100% | Synonymous variant | 0.033 |
| BATF2 | rs42191303 | 29:43828428 | C/T | C, 100% | C, 20% | Intron variant | 0.001 |
| BLNK | rs42088770 | 26:17382354 | A/T | A, 100% | A, 50% | Intron variant | 0.033 |
| BLNK | rs110491800 | 26:17395942 | A/G | A, 50% | A, 100% | Intron variant | 0.033 |
| BLNK | rs110241837 | 26:17398172 | G/T | G, 0% | G, 70% | Intron variant | 0.003 |
| BLNK | rs109825977 | 26:17398543 | A/G | A, 0% | A, 60% | Intron variant | 0.011 |
| BLNK | rs209836657 | 26:17398630 | G/C | G, 0% | G, 70% | Intron variant | 0.003 |
| BLNK | rs42088798 | 26:17399306 | G/C | G, 0% | G, 70% | Intron variant | 0.003 |
| BLNK | rs385916156 | 26:17399758 | T/A | T, 0% | T, 60% | Intron variant | 0.011 |
| BLNK | rs211039227 | 26:17401401 | T/A | T, 0% | T, 60% | Intron variant | 0.011 |
| BLNK | rs42088814 | 26:17401969 | A/G | A, 100% | A, 40% | Intron variant | 0.011 |
| BLNK | rs42088815 | 26:17402059 | T/C | T, 100% | T, 50% | Intron variant | 0.033 |
| BLNK | rs42084078 | 26:17419883 | A/G | A, 0% | A, 50% | Missense variant | 0.033 |
| BLNK | rs135453434 | 26:17427529 | C/T | C, 100% | C, 50% | Intron variant | 0.033 |
| BLNK | rs42084065 | 26:17428014 | T/C | T, 100% | T, 50% | Intron variant | 0.033 |
| BLNK | rs132877528 | 26:17431964 | C/T | C, 0% | C, 50% | Intron variant | 0.033 |
| BLNK | rs134560601 | 26:17432163 | A/G | A, 0% | A, 60% | Intron variant | 0.011 |
| IL18R1 | rs109078612 | 11:7153863 | T/C | T, 0% | T, 60% | Intron variant | 0.011 |
| IL18R1 | rs109700098 | 11:7169952 | T/C | T, 0% | T, 60% | Intron variant | 0.011 |
| IL18R1 | rs109755291 | 11:7179544 | C/T | C, 0% | C, 60% | Missense variant | 0.011 |
| ITK | rs109137099 | 7:70923893 | T/C | T, 80% | T, 20% | Intron variant | 0.023 |
| THEMIS | rs135858596 | 9:66782892 | C/A | C, 30% | C, 90% | Intron variant | 0.020 |
| THEMIS | rs207702093 | 9:66756813 | C/T | C, 100% | C, 50% | Intron variant | 0.033 |
| EBF1 | rs207972417 | 7:72475725 | C/T | C, 100% | C, 40% | Intron variant | 0.011 |
| EBF1 | rs207622846 | 7:72477936 | T/C | T, 100% | T, 50% | Intron variant | 0.033 |
| EBF1 | rs209147903 | 7:72478125 | G/A | G, 100% | G, 40% | Intron variant | 0.011 |
| EBF1 | rs211282271 | 7:72478236 | T/C | T, 100% | T, 50% | Intron variant | 0.033 |
| EBF1 | rs384133035 | 7:72481066 | A/G | A, 100% | A, 50% | Intron variant | 0.033 |
| EBF1 | rs41656033 | 7:72582112 | G/C | G, 100% | G, 30% | Intron variant | 0.003 |
| EBF1 | rs132998336 | 7:72588676 | G/A | G, 90% | G, 30% | Intron variant | 0.020 |
| EBF1 | rs135578882 | 7:72616057 | C/T | C, 100% | C, 40% | Intron variant | 0.011 |
| EBF1 | rs43524161 | 7:72701165 | C/G | C, 50% | C, 0% | Intron variant | 0.033 |
| EBF1 | rs29027619 | 7:72710782 | G/C | G, 70% | G, 10% | Intron variant | 0.020 |
*Allele frequency in non-shedders, total frequency of two alleles are 100%.
**Allele frequency in super-shedders, total frequency of two alleles are 100%.