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Effect of I K1 injection on maximal diastolic potential (MDP) and maximal upstroke velocity (dV/dt max) in hiPSC-CMs. a Representative example of action potential traces recorded from hiPSC-CMs upon injection of increasing magnitudes of simulated I K1 using dynamic clamp. Impact of I K1 injection at different amplitudes on MDP and dV/dtmax is shown in panels b and c, respectively (*p < 0.05). Figure reproduced from [68]
