Table 3.
Figure no. | Description | Distribution of molecular scores in quadrants | ||||
---|---|---|---|---|---|---|
| ||||||
Top right quadrant (C+M+) | Top left quadrant (C+M−) | Bottom right quadrant (C−M+) | Bottom left quadrant (C−M−) | p-value | ||
Figure 6(A) | ABMR—biological replicates | 25 | 39 | 5 | 5 | 0.51 |
Figure 6(B) | ABMR—cortex/medulla | 9 | 25 | 11 | 11 | 0.07 |
Figure 6(C) | ABMR—reference set | 354 | 745 | 30 | 61 | 0.88 |
Figure 6(D) | TCMR—biological replicates | 13 | 51 | 2 | 8 | 0.98 |
Figure 6(E) | TCMR—cortex/medulla | 4 | 30 | 5 | 17 | 0.28 |
Figure 6(F) | TCMR—reference set | 166 | 933 | 6 | 85 | 0.03 |
Figure 6(G) | Rejection—biological replicates | 39 | 25 | 7 | 3 | 0.58 |
Figure 6(H) | Rejection—cortex/medulla | 10 | 24 | 12 | 10 | 0.06 |
Figure 6(I) | Rejection—reference set | 534 | 565 | 38 | 53 | 0.21 |
Figure 7(A) | IRRATs—cortex/medulla | 21 | 13 | 14 | 8 | 0.89 |
Figure 7(B) | IRRATs—biological replicates | 39 | 25 | 6 | 4 | 0.96 |
Figure 7(C) | IRRATs—reference set | 456 | 643 | 37 | 54 | 0.88 |
ABMR, antibody-mediated rejection; IRRATs, acute kidney injury transcripts; TCMR, T cell–mediated rejection.
The cutoffs in Figure 1 divide the data into high cortex (“C+”) versus low cortex (“C−”) and molecular score positive (“M+”) or negative (“M−”), giving four quadrants: C+M+, C+M−, C−M+, and C−M−.