Table 3.

Univariate and multivariable analysis of predictive factors for mortality in severe hypoxic hepatitis

Variable	Univariate analysis		Multivariable analysis
	HR (95%CI)	P value	HR (95%CI)	P value
Age	1.03 (0.99-1.06)	0.069	1.07 (0.99-1.14)	0.056
Male gender	0.29 (0.10-0.83)	0.021	0.17 (0.03-1.19)	0.074
Precipitating hypotensive episode	3.21 (1.02-10.14)	0.046	4.40 (0.47-40.9)	0.192
Albumin	0.88 (0.80-0.96)	0.004	0.83 (0.71-0.96)	0.015
ALT	1.00 (0.99-1.00)	0.054	1.00 (1.00-1.00)	0.609
Creatine kinase	1.00 (1.00-1.00)	0.032	1.00 (1.00-1.00)	0.068
Creatine kinase MB	1.02 (0.99-1.05)	0.122	0.98 (0.94-1.02)	0.330
Troponin T	1.39 (0.88-2.16)	0.178	1.29 (0.74-2.27)	0.374
ALT/AST ratio_D11	0.65 (0.35-1.19)	0.160	0.22 (0.04-13.1)	0.465

¹Ratio of the ALT to AST at the first documentation of either ALT or AST > 3000 U/L. ALT: Alanine transaminase; AST: Aspartate transaminase.