Table 2.
Severity predictors, imaging findings, and clinical outcomes among acute pancreatitis patients with isolated organ failure, multi-organ failure, and no persistent organ failure n (%)
| IOF | MOF | P value | No OF | P value | |
| n = 43 | n = 68 | n = 389 | |||
| SIRS score on admission ≥ 2 | 23 (53.5) | 45 (66.2) | 0.18 | 107 (27.5) | < 0.001 |
| SIRS score at 48 h of admission ≥ 2 | 26 (60.5) | 52 (76.5) | 0.07 | 84 (21.6) | < 0.001 |
| Mean IVF the first 24 h in liters (SD) | 4.38 (1.98) | 5.04 (1.79) | 0.41 | 3.79 (1.5) | 0.23 |
| ICU admission | 36 (83.7) | 68 (100) | 0.001 | 50 (12.9) | < 0.001 |
| Median ICU LOS in days (IQR) | 6 (2-14.4) | 18.5 (10-35) | < 0.001 | 0 | < 0.001 |
| Need for nutritional support | 38 (88.4) | 58 (85.3) | 0.64 | 80 (20.6) | < 0.001 |
| Pancreatic necrosis1 | 28/39 (71.8) | 45/54 (83.3) | 0.18 | 80/251 (31.9) | < 0.001 |
| Infected necrosis1 | 5/39 (12.8) | 21/54 (38.9) | 0.006 | 11/164 (6.7) | 0.2 |
| Need for drainage or debridement | 13 (30.2) | 38 (55.9) | 0.008 | 31 (8) | < 0.001 |
| Extra-pancreatic infections | 8 (18.6) | 30 (44.1) | 0.006 | 27 (6.9) | 0.008 |
| Median LOS in days (IQR) | 20 (16-32) | 37 (25-53) | < 0.001 | 6 (4-9) | < 0.001 |
| Mortality | 0 | 22 (32.4) | < 0.001 | 0 |
1
Denominators reflect number of patients with available contrast-enhanced computed tomography scan. P values: 1st column reflects comparison of IOF to MOF, and 2nd column reflects comparison of IOF to OF. AP: Acute pancreatitis; IOF: Isolated organ failure; MOF: Multi-organ failure; OF: Organ failure; SIRS: Systemic inflammatory response syndrome; IVF: Intravenous fluids; ICU: Intensive care unit; LOS: Length of stay; IQR: Interquartile range.